Prolactin reference values – in this post I wanted to compare the reference values presented in the method leaflets of various diagnostic test manufacturers. The post is intended to be informative.
Remember that laboratory test results should be interpreted with reference to the values provided by the laboratory. This post is for educational purposes.
What are the standards for prolactin? What are the ranges of reference values for prolactin? You can find the answer in the table below.
Prolactin reference values – summary table
Values refer to the determination of serum prolactin levels.
| Manufacturer | ROCHE1 | SIEMENS2 | ABBOTT3 | KIEĆ4 | BECKMANN5 | MAYO6 | CALIPER 7 | KRAWCZYŃSKI 8 |
|---|---|---|---|---|---|---|---|---|
| Prolactin – reference range ADULTS ng/mL | WOMEN not pregnant 4.79-23.3 MEN 4.04-15.2 | WOMEN not pregnant 2.8–29.2 pregnant 9.7–208.5 postmenopausal 1.8–20.3 MEN 2.1–17.7 | WOMEN 5.18-26.53 MEN 3.46-19.40 | WOMEN 5.97-29.94 MEN 4.61-21.43 | WOMEN premenopausal 3.34-26.72 postmenopausal 2.74-19.64 MEN 2.64-13.13 | WOMEN 4.0-15.2 MEN 4.8-23.3 | NO DATA | WOMEN <30 MEN <30 |
| Prolactin – reference range ADULTS μIU/ml | WOMEN not pregnant 102-496 MEN 86-324 | WOMEN not pregnant 59–619 pregnant 206–4420 postmenopausal 38–430 MEN 45–375 | WOMEN 108.78-557.13 MEN 72.66-407.40 | WOMEN 127-637 MEN 98-456 | WOMEN premenopausal 71-566 postmenopausal 58-416 MEN 56-278 | WOMEN 84.8 – 322 MEN 102-494 | NO DATA | WOMEN <620 MEN <620 |
| Prolactin – reference range CHILDREN ng/mL | NO DATA | NO DATA | NO DATA | NO DATA | NO DATA | NO DATA | CHILDREN 4 – 30 days 12.6-213 30 days – 1 year 6.3-114 1 year – 19 years 4.2-23 | NEWBORNS <81 INFANTS <30 OLDER CHILDREN <17 |
| Prolactin – reference range CHILDREN μIU/ml | NO DATA | NO DATA | NO DATA | NO DATA | NO DATA | NO DATA | CHILDREN 4 days – 30 days 264-4468 30 days – 1 year 132-2388 1 year – 19 years 88.1-484 | NEWBORNS <1720 INFANTS <640 OLDER CHILDREN <360 |
Legend: m – month, d – days, y – years
Correlation of prolactin reference values
Below I present some infographics on the correlation of reference values for prolactin concentrations.
Graph 1. Prolactin concentration dependence between pregnant and non-pregnant women [2].
Graph 2: Dependence of prolactin concentrations in pre- and postmenopausal women [2].
Graph 3. Age correlation between prolactin concentrations in children [7].
Graph 4: Gender dependence of prolactin concentration [2].
Remember that when you want to monitor the concentration of a parameter, the test should be performed in the same laboratory, using the same method. This is very important for observing changes.
Downloadable tables and graphs
I have prepared for you a list of reference values in printable form.
- prolactin – reference values – table
- prolactin – correlation of reference values – table
Sources:
- Elecsys Prolactin II, Cobas e801, 2022-07, V 6.0 Polski
- Prolaktyna (PRL), Siemens Healthineers, Atellica CI Analyzer, Rev. 04, 2023-03
- Prolactin Reagent Kit, Abbott Alinity i, luty 2018
- Diagnostyka laboratoryjna z elementami biochemii klinicznej, Aldona Dembińska-Kieć, Jerzy W.Naskalski, Wydanie III, 2009
- Access Prolactin, Access Immunoassay Systems, Instructions For Use A83772 L, April 2020
- Pediatric Catalog, Mayo Clinic Laboratories, https://pediatric.testcatalog.org from 11.07.2023
- https://caliper.research.sickkids.ca/#/ from 17.07.2023
- Norma kliniczna w pediatrii, Marian Krawczyński, Wydawnictwo Lekarskie PZWL 2005
Disclaimer: This page is for informational purposes only. Conversion rates have been compiled based on publicly available information. All information should be confirmed and verified. The data on the site is not a substitute for professional medical advice. Any information, result, conversion should be consulted with a doctor.